Ethic
The bioequivalence study has been registered on ClinicalTrials.gov (No.:NCT04885660, retrospectively registered in May 2021) and been approved bythe Medical Ethics Committeeof the Affiliated Hospital of Qingdao University (No.: QYFYEC 2018–055-01). The study was conducted in accordance with the Declaration of Helsinki, Good Clinical Practice (GCP) and applicable lawsand regulationsof China National Medical Products Administration(NMPA).Writteninformed consent wasobtained from all subjects before their participation in the study.