Figure 3. IL-25 induces eosinophils recruitment in vivo.
Mice were instilled intranasally with 100ug/40μL murine recombinant IL-25 or 40μL PBS. After 1 day, mice were sacrificed for analyzing lung eosinophils. Schematic representation as in (A). (B) Flow plots showing the extent of eosinophils (viable CD45+SiglecF+CD11c-) infiltration into the lungs of mice after IL-25 exposure. (C) Quantification of eosinophils infiltration after IL-25 exposure. Each dot represents a mouse. n=5, **p<0.01, Unpaired Student’s t test.