Figure 5. IL-25 deficiency reduces eosinophils chemotaxis after HDM sensitization.
(A) Schematic representation of HDM-primed eosinophils chemotaxis for focusing on the early sensitization period.
(B-C) Flow plots showing the percentage (B) and qualification (C) of eosinophils infiltration into lungs after HDM or PBS sensitization of WT mice at indicated times.
(D) Schematic representation of mice 3 days after HDM-priming.
(E-H) Flow plots showing the percentage and qualification of eosinophils infiltration into lungs (E, F) and airways (G, H) of WT and Il25-/- mice 3 days after HDM or PBS sensitization. n=4 for F; n=6 for H
Unpaired Student’s t test (C, D, E, F, G and H) , ns, no significant difference, *p<0.05 **p<0.01 ***p<0.01