Side effects
The self-developed side effect burden questionnaire is based on the
Lareb Intensive Monitoring (LIM) system and consists of two parts. In
part one patients are asked if they experience side effects that they
relate to DOAC use and secondly if they recognize 8 typical side effects
attributed to DOAC use. In part two the side effect burden for every
reported side effect was rated on a 5-point Likert Scale from 0 (no
burden) to 5 (very high burden). A low side effect burden is defined as
either no or only minor burdensome side effects, whereas high burden is
defined as moderate to very burdensome side effects. Both the percentage
of patients reporting side effects as the sum side effect burden per
patient are calculated. The side effect burden questionnaire measures
the experiential aspect of side effects whereas BMQ question 11 measures
the cognitive aspect of side effects.