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\begin{document}

\title{The Utility of Respiratory Rate Index in High-Flow Nasal Cannula Oxygen
Therapy for COVID-19 Pneumonia}



\author[1]{Kai Wang}%
\author[1]{Jihong Zhu}%
\author[1]{Weibo  Gao}%
\author[1]{Li  Ma}%
\author[1]{Baoping  Cao}%
\author[1]{Xueying   Fu}%
\author[1]{Miao   Shi}%
\affil[1]{Peking University People's Hospital}%


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  \date{May 25, 2024}


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\begin{abstract}
A useful solution for the management of COVID-19 pneumonia has been
identified: oxygen therapy delivered using a high-flow nasal cannula
(HFNC). Improved oxygenation and respiratory support are provided by
this treatment. In patients who are being associated with HFNC for
COVID-19 pandemic, this investigation aims to define whether or not the
respiratory rate index (RRI) is useful as an early indicator of how well
the treatment is working and how the patient would fare clinically. This
study retrospectively examines COVID-19 pneumonia patients maintained
with HFNC in a clinical setting. Data on respiratory rate (RR) was used
to calculate a respiratory rate index that considered both rate and
pattern. Fast respiratory rate index reductions during the first therapy
improved oxygenation and reduced mechanical ventilation. The score
predicted pharmaceutical responsiveness before other clinical markers
made meaningful improvements. RR, OSIXR, and ROX index are questionable
ventilator prevention strategies. We treated 128 COVID-19 respiratory
failure patients who needed oxygen. A 64 HFNC-treated patients were
retrospectively studied. The HFNC group was those who converted from the
HFNC therapy to conventional oxygen therapy (COT), while the COT
treatment was those who converted from the HFNC group to Non-invasive
ventilation (NIV). HFNC patients were successful (24 of 64 (62\%)). HFNC
success had a considerably greater univariate RR improvement than COT.
Logistic regression analysis (LRA) adjusted for respiratory development,
age, and ROX index \textgreater{}6.66 showed that an enhanced RR
predicted success. HFNC achievement groups had significantly lower COT
durations than COT groups.%
\end{abstract}%



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\verb`4med-03_Paper_v1_22.08.2023.docx`  available at \url{https://authorea.com/users/752672/articles/723271-the-utility-of-respiratory-rate-index-in-high-flow-nasal-cannula-oxygen-therapy-for-covid-19-pneumonia}

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