Acknowledgments and funding sources
We thank Guillermo Medrano for help with mouse procedures and Vanessa Bermeo for assisting with tissue sections and staining. Birgit Hockenjos for analysing JunΔli, HBVTg liver samples, Stefanie Stolzlechner for IHC troubleshooting and Sophia Derdak from the Core Facilities of the MUV, a member of the Vienna Life-Science Instruments initiative, for analysis of bulk RNA-seq data. We are grateful to the CNIO Molecular Imaging, Mouse Genome Editing, Histopathology and Genomics Core Units for efficient service. We are very grateful to Drs. Douglas Hanahan, Kazuhiko Matsuoka, Robert Eferl, Nabil Djouder, Esteban Gurzov, Emilio Casanova and to the members of the Wagner laboratory for comments and discussions. The Wagner laboratory is supported by the ERC (AdG 2016-741888-CSI-Fun), a H2020 – MSCA grant (ITN 2019-859860-CANCERPREV) and the MUW.