Future Directions
Our examination of existing medical literature on ion channelopathies and their impact on Hispanic/Latino and Indigenous populations indicates that international and inter-institutional studies have identified genetic and environmental factors in these groups (Table 1 ). However, there is a need for additional research to establish a comprehensive consensus on the effects of genetic variants across various ethnic subgroups. This understanding can contribute to more targeted clinical treatments. For example, genome-wide association studies in Native American and Aboriginal communities could highlight SNPs in LQTS or other ion channelopathies, as was illustrated in the Hispanic community. Conversely, multigenerational studies conducted in Hispanic/Latino communities could provide a more complete picture of hereditary LQTS. The Hispanic/Latino and Indigenous demographics comprise a significant portion of the general population, and as such, more extensive research studies have to be conducted to bridge healthcare disparities surrounding cardiac ion channelopathies in these underserved populations.