1. INTRODUCTION
Thromboembolism is a common and potentially life-threatening
complication that can arise from various medical conditions, including
malignancy and a spectrum of benign diseases. Adenomyosis, characterized
by the presence of endometrial glands and stroma within the myometrium,
is a benign uterine disorder that typically presents in middle-aged
postpartum women with symptoms of menorrhagia, dysmenorrhea, and chronic
pelvic pain. The true prevalence of adenomyosis remains unknown,
although estimates derived from patients referred for pelvic imaging
suggest a range of 20% to 34%.1 The association
between adenomyosis and thrombosis was first described by Kupryjanczyk
in 1991.2 Subsequently, several isolated case reports
and case series have documented the occurrence of ischemic
stroke3-20 and pulmonary embolism
(PE)21, 22 in patients with adenomyosis, suggesting a
possible association with hypercoagulability induced by this disorder.
However, there are few reports of cases complicated by isolated deep
vein thrombosis (DVT). 23, 24 In this report, we
present a case of isolated distal deep venous thromboembolism (IDDVT) in
a patient with a 1.5-year history of adenomyosis. We also conducted a
comprehensive literature review to explore the clinical features,
treatment approaches, and prognosis of thrombotic complications
associated with this condition.