Results
A total of 24 rat, divided into 3 groups of 8 rat each, were observed
throughout the duration of the experiment. Table 1 shows the baseline
ECHO parameters of the three groups. There is no difference between the
groups when comparing echo parameters at baseline. Table 2 shows the
echo parameters of the control group on days 0, 15 and 30, table 3 shows
the dapagliflozin and table 4 shows the sacubitril/valsartan group.
When comparing baseline data, there was no significant difference
observed in the performance of rotarods and their corresponding weights.
Table 5 shows the change in the rat’s weight over the course of the
experiment, and Table 6 shows the results from the rotarod follow-ups.
Table 7 shows the median swimming times of each group during the
swimming sessions throughout the experiment. Starting from the 9th
swimming session, there was a noticeable difference in the swimming
times between the groups. Figure 1 displays the average swimming
performance of the three groups. Table 8 shows the comparison of
sacubitril/valsartan with the control group, and table 9 shows the
comparison of dapagliflozin with the control group.