The two TA-receptor mutants TyrRf05682 and honoka showed a decreased sugar response and an increased survival comparable to tßhnM18 mutants. In contrast, the double mutant TyrII-TyrR∆124 showed an increase in survival but a normal sugar response, while TyrRII∆29 shows normal survival but a decrease in sugar response. Finally, oamb286 mutants lived longer than their control, in contrast to a previously published report Erion 2012, while the oamb584 allele showed no phenotype. The receptor mutant data suggest that flies can exhibit a wild type survival simultaneously with a lower sugar response (TyrRII∆24), or a higher survival simultaneously with a wild type sugar response (oamb286, double mutant TyrII-TyrR∆124), suggesting that starvation affects sugar responsiveness and survival via different but amine-dependent pathways.