loading page

Systematic review and meta-analysis of the seroprevalence of West Nile virus in equids in Europe between 2001 and 2018
  • +1
  • MARINE METZ,
  • Olaolu Olufemi,
  • Janet Daly,
  • Marta Barba
MARINE METZ
CEU Universidad Cardenal Herrera
Author Profile
Olaolu Olufemi
University of Nottingham
Author Profile
Janet Daly
School of Veterinary Medicine and Science, University of Nottingham,UK
Author Profile
Marta Barba
CEU Universidad Cardenal Herrera
Author Profile

Abstract

There is some evidence that West Nile virus (WNV), which causes encephalomyelitis in equids, is an emerging disease in Europe. The aim of this study was to perform a systematic review and meta-analysis to determine the seroprevalence of West Nile virus in equids in European countries between 2001 and 2018. Two electronic databases, PubMed and Scopus, were searched for relevant publications published from 2001 to 2018 using predetermined keywords. A total of 1484 papers was initially found. After applying the eligibility criteria, 39 papers were finally included in the systematic review. Analysis of 28,089 equids from 16 European countries revealed a pooled seroprevalence of 8% (95% CI 5–12%, P<0.001, I2 = 99.3%) in Europe. The pooled seroprevalence was slightly higher in Mediterranean basin countries than other countries and when calculated for samples collected between 2001 and 2009 compared to 2010 to 2018. Differences in study design (e.g. sampling associated with recent outbreaks of WNV) contributed to a high degree of variability among studies. Further studies with harmonized study design and reporting of the results are recommended to better estimate and monitor European seroprevalence of West Nile virus in equids.

Peer review status:UNDER REVIEW

24 Aug 2020Submitted to Transboundary and Emerging Diseases
25 Aug 2020Submission Checks Completed
25 Aug 2020Assigned to Editor
26 Aug 2020Reviewer(s) Assigned
13 Sep 2020Review(s) Completed, Editorial Evaluation Pending
14 Sep 2020Editorial Decision: Revise Minor
17 Sep 20201st Revision Received
17 Sep 2020Submission Checks Completed
17 Sep 2020Assigned to Editor
17 Sep 2020Reviewer(s) Assigned