Risk factors for complications of implantable venous access port usage
among young pediatric patients with a solid tumor in China: a
single-center retrospective study
Abstract
Background and Objectives: This study aimed to evaluate the utilization
of totally implantable venous access ports (TIVAPs) and identify risk
factors for complications associated with their usage in young pediatric
patients with a solid tumor. Methods: We retrospectively investigated
the clinical characteristics and procedure records of all patients
admitted with a solid tumor who underwent TIVAP implantation and removal
as well as line patency maintenance in our clinic from 2016 to 2019 at
the Shanghai Children’s Medical Center. Results: Overall, 144 patients
were evaluated over 28,444 catheter days. There was a greater risk of
central line-associated bloodstream infection (CLABSI) in patients with
neuroblastoma who were older in age and whose body mass index was lower.
The rate of CLABSI was relatively increased in high-risk than low-risk
and intermediate-risk neuroblastoma according to the Children’s Oncology
Group (COG) classification system. There were no significant differences
in complications between the TIVAP implantation group and the combined
surgery group. Conclusions: Older age, lower BMI, and high COG risk are
great risk factors of CLABSI in patients with neuroblastoma, thus
requiring vigilant surveillance. Combining TIVAP insertion with biopsy
and/or resection surgery should be given due consideration.