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Cardiorespiratory complications in pediatric oncology patients with COVID-19 infection
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  • Peter Schoettler,
  • Paul Sue,
  • Tamra Slone,
  • Andrew Koh
Peter Schoettler
The University of Texas Southwestern Medical Center Department of Pediatrics
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Paul Sue
University of Texas Southwestern Department of Pediatrics
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Tamra Slone
University of texas Southwestern Medical Center
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Andrew Koh
UT Southwestern
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Abstract

The risk of the novel coronavirus disease 2019 (COVID-19) to pediatric oncology patients is unknown. Here, we report eight pediatric oncology patients receiving active cancer therapy that tested positive for COVID-19. Three developed severe cardiorespiratory symptoms (as defined by evidence of heart failure by echocardiogram and/or intubation secondary to respiratory failure), including one death as a result of COVID-19 infection. We identified prior anthracycline exposure and pre-COVID cardiac function as significantly associated with the development of severe cardiorespiratory complications. These data merit future and further investigation of risk factors for severe complications related to COVID-19 infections in pediatric oncology patients.