A case of herbal medicine induced toxic epidermal necrosis in a
hypergammaglobulinemic purpura of Waldenström patient
Abstract
We are reporting a case of toxic epidermal necrosis induced by herbal
medicine in a 54-year-old woman who had been diagnosed with primary
Sjogren’s syndrome for nine years and had discontinued all conventional
therapies for at least one year. Approximately two weeks prior to her
current admission, she developed crops of petechiae and purpuric macules
on her lower extremities, which are typical symptoms of
hypergammaglobulinemic purpura of Waldenström, and began taking herbal
medicine. The following day, she presented to us with a high fever and
new, generalized erythematous rashes over her face and trunk. She was
ultimately diagnosed with toxic epidermal necrosis induced by the herbal
medicine.