Introduction: The rating of perceived exertion (RPE) is a widely used method for monitoring the load during training, as it provides insight into the subjective intensity of effort experienced during exercises. Considering the role of brain in monitoring and perception of the effort, several studies explored the effect of transcranial direct current stimulation (tDCS) on RPE in different populations. The aim of current study is to review the studies investigated the effect of tDCS on RPE in three groups including healthy untrained people, physically active persons and athletes. Method: Nine databases were searched for papers assessing the effect of tDCS on RPE. The data of included studies were extracted and methodological quality examined using the risk of bias 2 (ROB2) tool. Thirty-three studies met the inclusion criteria. Results: According to the meta-analysis, active a-tDCS significantly decreased the RPE compared to the sham-stimulation. The a-tDCS could decrease the RPE when it was applied over M1 or DLPF. Regarding the measurement tool, Borg’s scale 6-20 and OMNI scale could show an improvement in RPE scale. Conclusion: A-tDCS is a promising technique that can decrease improve the RPE. M1 and DLPFC are suggested as the target area of stimulation. From the tools that measure the RPE, Borg’s RPE 6-20 and OMNI scale could better show the effect of a-tDCS.