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Electrochemical Cascade Annulation for the Synthesis of 3-Phenylsulfanylquinoline Derivatives Under Mild Conditions
  • +4
  • Ke Li,
  • Ming-Zhong Guo,
  • Zhuo Chen,
  • Hao-Ran Li,
  • Weisi Guo,
  • Ming Li,
  • Lin-Bao Zhang
Ke Li
Qingdao University of Science and Technology
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Ming-Zhong Guo
Qingdao University of Science and Technology
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Zhuo Chen
Qingdao University of Science and Technology
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Hao-Ran Li
Qingdao University of Science and Technology
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Weisi Guo
Qingdao University of Science and Technology
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Ming Li
Qingdao Univ Sci & Technol, State Key Lab Base Ecochem Engn, Coll Chem & Mol Engn, 53 Zhengzhou Rd, Qingdao 266042, Peoples R China
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Lin-Bao Zhang
Qingdao University of Science and Technology

Corresponding Author:[email protected]

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Abstract

An efficient electrochemical approach has been developed for the construction of 3-phenylsulfanylquinoline derivatives by treating phenylethynylbenzoxazinanones with aryl disulfide in an undivided cell. The protocol provided a convenient route to functionalized quinolines with good functional group tolerance. Moreover, it does not require any metal catalysts or additives, furnishing a series of biological quinolines in moderate to good yields.

Peer review status:UNDER REVIEW

31 Jan 2024Submitted to Chinese Journal of Chemistry
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03 Feb 2024Review(s) Completed, Editorial Evaluation Pending
03 Feb 2024Assigned to Editor
03 Feb 2024Submission Checks Completed
04 Feb 2024Reviewer(s) Assigned