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Porcine circovirus-like agents in sera of dogs and cats in China
  • +1
  • libin wen,
  • aihao mao,
  • jianping xie,
  • kongwang he
libin wen
Jiangsu Academy of Agricultural Sciences
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aihao mao
Jiangsu Academy of Agricultural Sciences
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jianping xie
Jiangsu Academy of Agricultural Sciences
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kongwang he
Jiangsu Academy of Agricultural Sciences
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Abstract

Porcine circovirus-like agents comprise two types of viruses: porcine circovirus-like viruses (P1, P2, P3, and P4) and porcine circovirus-like mini agents (PCVL258, PCVL264, PCVL201, and PCVL347). Of these, P1 has been identified in pigs, cattle, goats, and rabbits in China; P2, P3, P4, PCVL258, and PCVL264 have been identified in pigs; and PCVL201 and PCVL347 have been identified in cattle. The purpose of this study was to determine whether dogs and cats have been exposed to porcine circovirus-like agents. We screened 158 serum samples from diseased dogs and 41 from cats in China by PCR and nucleotide sequencing. In dogs, approximately 18% (n=28) were positive for P1, 17% (n=26) for PCVL258, and 9% (n=14) for PCVL264; in cats, 17.1% (n=7) were positive for P1, 9.8% (n=4) for P4, and 14.6% (n=6) for PCVL258. The P1 genomes in this study consisted of 648 nucleotides (nt), and shared 96.8 to 100% nt identity with other P1 genomes in GenBank. The P4 genome shared 98.3 to 100% nt identity with other reported P4 genomes, and PCVL258 and PCVL264 showed 100% nt identity with previously reported genomes. To our knowledge, this is the first report on molecular characterization of porcine circovirus-like agents in dogs and cats. Further studies are needed to clarify the epidemiology, evolution, and pathogenesis of porcine circovirus-like agents in dogs and cats.