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Why are cancer patients with COVID-19 more likely to develop severe events?
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  • Jianping Bi,
  • Yajie Wang,
  • Tingting Nie,
  • Vivek Verma,
  • Guoliang Pi,
  • Changchun Chen,
  • Guowu Jiang,
  • Guang Han
Jianping Bi
Hubei Cancer Hospital
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Yajie Wang
People's Hospital of Dongxihu District
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Tingting Nie
Hubei Cancer Hospital
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Vivek Verma
Allegheny General Hospital
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Guoliang Pi
Hubei Cancer Hospital
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Changchun Chen
Hubei Cancer Hospital
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Guowu Jiang
Hubei Cancer Hospital
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Guang Han
Hubei Cancer Hospital
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Peer review status:UNDER REVIEW

10 May 2020Submitted to International Journal of Clinical Practice
12 May 2020Assigned to Editor
12 May 2020Submission Checks Completed
18 May 2020Reviewer(s) Assigned

Abstract

Many articles have reported that cancer patients are more susceptible to COVID-19 pneumonia and cancer patients with COVID-19 seem to be more often tend to develop severe events. In these studies of infected cancer patients, factors associated with a higher risk of developing severe events included age, baseline fragility, and anti-tumor treatment. However, specific reasons regarding why infected patients with cancer have a higher probability of severe events compared to non-cancer infected patients remain unclear. Thus, we sought to study one particular factor to determine a potential associative effect: differences in Computed tomography (CT) findings. In our study,we found that cancer patients represent a special population which multiple lobes of the lungs were more susceptible to infection by the SARS-CoV-2, and thus were more likely to be transferred from mild illness to severe, should be deserved more intensive attention during the SARS-CoV-2 pandemic.