loading page

BACTEREMIA BY CARBAPENEMASE PRODUCING ENTEROBACTERIACEAE CAN BE REDUCED BY MEASURES OF HOSPITAL INFECTION CONTROL
  • +12
  • Desiree Caselli,
  • Antonella Colombini,
  • Daniele Zama,
  • Elio Castagnola,
  • Paola Muggeo,
  • Milena La Spina,
  • Katia Perruccio,
  • Raffaela De Santis,
  • Francesca Carraro,
  • Federico Mercolini,
  • Mariagrazia Petris,
  • Daniela Onofrillo,
  • Rosamaria Mura,
  • Valentina Barretta,
  • Simone CesaroOrcid
Desiree Caselli
1. Infectious Diseases, Giovanni XXIII Children Hospital, Azienda Ospedaliero Universitaria Consorziale Policlinico
Author Profile
Antonella Colombini
MBBM Foundation, University of Milano-Bicocca, Monza, Italy
Author Profile
Daniele Zama
Department of Pediatrics, Pediatric Oncology and Haematology Unit "Lalla Seràgnoli", Sant' Orsola Malpighi Hospital, University of Bologna
Author Profile
Elio Castagnola
Infectious Diseases Unit, IRCCS Istituto Giannina Gaslini, Genova
Author Profile
Paola Muggeo
University Hospital of Policlinico Bari
Author Profile
Milena La Spina
Policlinico di Catania
Author Profile
Katia Perruccio
Pediatric Oncology and Hematology Section
Author Profile
Raffaela De Santis
Unit of Pediatrics
Author Profile
Francesca Carraro
Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, AOU Città della Salute e della Scienza, Regina Margherita Childrens Hospital
Author Profile
Federico Mercolini
Azienda Ospedaliera di Bolzano
Author Profile
Mariagrazia Petris
3. Pediatric Hematology-Oncology
Author Profile
Daniela Onofrillo
Santo Spirito Hospital,
Author Profile
Rosamaria Mura
Paediatric Haematology-Oncology, Ospedale Pediatrico Microcitemico, Cagliari, Italy
Author Profile
Valentina Barretta
Pediatric Hematology-Oncology, Azienda Ospedaliera Universitaria Integrata
Author Profile
Simone Cesaro
Orcid
Pediatric Hematology and Oncology Unit, Department of Pediatrics, Azienda Ospedaliera Universitaria Integrata, Verona
Author Profile
Medium

Abstract

Carbapenemase-producing Enterobacteriaceae (CPE) , multidrug resistant (MDR) threatens children undergoing chemotherapy. A previous survey reported increase of bloodstream infections and colonization in a 2 year-observation time. To test the efficacy of the measures put in place , a second survey was performed. Data were collected from 13 Italian pediatric cancer centers of AIEOP network. The colonization rate per 1000 hospitalizations days was 0.5 (0.37-0.65) not different from the 0.48 rate (0.36-0.63) observed previously .Yet the 0.12 rate of bacteriemia (0.07-0.21) compared favorably with the 0.42 (0.31-0.57) observed. The awareness of colonization status allowed reducing CPE related morbidity and mortality.