Clinical and microbiological evaluation of the oral cavity of patients
with Langerhans Cell Histiocytosis.
Abstract
The Langerhans Cell Histiocytosis (LCH) is a disease characterized by
the clonal proliferation of Langerhans cells. Patients with this
diagnosis can present several manifestations in the oral cavity
frequently found are bone lesions and periodontitis. The diagnosis is
made with histological and immunohistochemical tests and the main form
of treatment is chemotherapy. OBJECTIVE: To evaluate the presence of
pathogenic bacteria, bone, dental conditions and manifestations in the
oral cavity. METHODS: For this, a study was carried out with patients
with LCH, they were submitted to oral swab, simplified periodontal
examination (PSR), and panoramic radiography. RESULT: It was found that
36.8% of patients had pathogenic bacteria such as Staphylococcus aureus
(10.5%). The PSR showed that 73.6% of the patients had a probing depth
of the gingival sulcus of 3 mm or more in the maxilla region and 63.1%
in the mandible (moderate periodontitis). The patients presented varied
manifestations on the radiograph, such as veiling of the maxillary
sinuses (33.3%). CONCLUSION: As it is a disease that affects the oral
cavity, it is important that the dentist knows its manifestations and
can be diagnosed and treated early in order to reduce mortality,
morbidity and promote quality of life for patients.