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Ten-year Trends in the Incidence of Microtia: A Nationwide Population-based Study from Taiwan
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  • Yen-Fu Cheng,
  • Sudha Xirasagar,
  • Tsai-Ching Liu,
  • Nai-Wen Kuo,
  • Herng-Ching Lin
Yen-Fu Cheng
Taipei Veterans General Hospital
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Sudha Xirasagar
University of South Carolina
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Tsai-Ching Liu
Taipei Medical University
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Nai-Wen Kuo
Taipei Medical University
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Herng-Ching Lin
Taipei Medical University

Corresponding Author:[email protected]

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Abstract

Objective: The aim of this study was to analyze the 10-year secular trends in the incidence of microtia and/or anotia from 2008 to 2017 using nationwide population-based data. Study design: A cross-sectional study Setting: Taiwan Participants: Patient data were retrieved from Taiwan’s National Health Insurance Dataset, after identifying 1,152 children aged ≤1 year with a first-time diagnosis of microtia or anotia between January 2008 and December 2017. The annual microtia-anotia incidence rate was the sum of new microtia-anotia cases in a year divided by total infant population in the year. Method: We used the annual percent change (APC) to study the secular trend in microtia-anotia incidence rate. Results: The annual incidence rate of microtia-anotia averaged across the 10-year period was 57.7 per 100,000 infants (standard deviation=8.6). The annual incidence rates of microtia and anotia were 53.3 and 4.4 per 100,000 infants, respectively, during this period. Furthermore, female infants had a higher incidence than males (63.3 vs. 52.4 per 100,000). The incidence of microtia-anotia gradually decreased between 2008 and 2017 with an APC of -5.64% (95% CI= -9.31%~-1.18%, p=0.004). Since 2011, females had a significantly higher annual incidence rate of microtia-anotia than males. Conclusions: The incidence of microtia-anotia was 57.7 per 100,000 infants in Taiwan, which declined during the study period 2008-2017. The female-to-male incidence ratio was 1.21:1.