A Novel Case of Concurrent T-cell and Early T-cell Lymphoblastic
Lymphoma in an Adolescent Female: A Brief Report
Abstract
In the context of an evolving understanding of early T-cell precursor
(ETP) lymphoma and leukemia, we present a case of concurrent T cell
lymphoblastic lymphoma and ETP lymphoma in an adolescent female. To our
knowledge, this represents the first reported case of both lymphoblastic
lymphoma and ETP lymphoma as distinct and conjoined components of the
same neoplasm. As an exception to current literature, our patient had
only ETP lymphoma with no marrow involvement. Her ETP component remained
viable following induction, supporting ETP resistance to chemotherapy.
The patient remains in remission 4 years post allogeneic matched sibling
donor bone marrow transplant.