Effects of COX 1-2 Inhibitors on Prevention of Rocuronium Injection
Pain: Controlled, Randomised, Double Blind Study
Abstract
Purpose : Rocuronium bromide is a painful agent while general anesthesia
induction. The aim of the study is to investigate the effects of cox
inhibitors as a resque agent against the rocuronium pain Methodology :
Sixty patients enrolled for the general anesthesia enrolled in this
study. Patients were allocated into two groups (Group 1: Dexkethoprofen
group, Group 2: Control group) .Pain was evaluated by during rocuronium
injection, patients were scored by a scale showed below. 0;No movement
response to injection 1;Mild movement response to injection 2;Hand
withdrawal response to injection 3;Arm withdrawal response to injection
We also evaluated the pain with 2 questions when the patient was in the
recovery room.Question 1.What was the last feeling before you fall into
sleep? and question 2. Did you feel any pain on your hand during
medication injection for anesthesia? Results:There were differences
between the groups in terms of total pain score for example in group 1
there were 16 (53%) patients who did not make any movement during
rocuronium injection while there were 22 (73%) patients in group
2.There was significant difference in injection rocuronium bromide pain
between group 1: dexkethoprofen group, Group 2: control group in terms
of the answer to the second question.Patients felt less pain than the
control group. Conclusion:The effect of cox inhibitors on rocuronium
pain was seen in our study but check is also effective in reducing pain
in vascular width.