This hypothesis explores the possibility of a function that describes how the effective mass of a particle changes over time during a quantum process. We introduce a Temporal Mass Function, \(m(t)=m_0e^{-λt}\) , to reflect changes in the energy and properties of the particle, particularly in the context of deferred annihilation. Substituting this function into Einstein's equation, \(E=mc^2\) , we obtain a new energy-time equation that shows how the energy of the particle changes due to the variation of its mass. The temporal derivative of this equation reveals that the rate of change of the particle's energy decreases over time, suggesting a novel quantum interpretation of annihilation. Furthermore, we propose replacing the constant speed of light, , with a constant representing the Universe's expansion speed, , leading to a reformulation of the mass-energy equation as . This approach suggests that a particle's energy could be linked to the expansion of space itself, raising significant questions about the relationship between mass, energy, and the expansion of the Universe in the quantum context.