THE EVALUATION INCREASE AMOUNT OF FeNO VOLUME BEFORE AND AFTER EXERCISE
IN OBESE ASTHMATIC PATIENTS
Abstract
ABSTRACT Objectives: The presence of exercise induced bronchospasm (EIB)
in children with obesity and asthma is known. The measurements of
fractional exhaled nitric oxide (FeNO) level in given breath are used as
an indicator of airway inflammation. It can be affected by exercise and
is high in patients with asthma. It is aimed to observe how much
exercise what is common cause of acute airway obstruction changes FeNO
in asthmatics in this study. Methods: FeNO was measured before/after
exercise in the groups of obese-asthmatic children, non-asthmatic but
obese children, the normal-weight children with asthma, non-asthmatic
and non-obese children between the ages of 5-18. Spirometric
measurements which are frequently used in asthma were compared with FeNO
levels. Results: The highest average of FeNO was seen in asthmatic-obese
group, the lowest mean of FeNO was found in healthy group. Non-asthmatic
but obese group had respiratory parameters increasing with exercise,
while FEV1/FVC was the lowest in the group with asthma-obesity and
decreased with exercise. Conclusions: There is a strong relationship
among FeNO and FEV1/FVC with asthma. The highest values of FeNO found in
asthma-obesity combined. It was seen that obesity increased inflamation
but didn’t increase EIB.