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Clinical characteristics of 182 pediatric COVID-19 patients with different severities and allergic status
  • +9
  • Hui Du,
  • Xiang Dong,
  • Jin-jin Zhang,
  • Yi-yuan Cao,
  • Mubeccel Akdis,
  • Pei-qi Huang,
  • Hong-wei Chen,
  • Ying Li,
  • Guanghui Liu,
  • Cezmi Akdis,
  • Xiao-xia Lu,
  • Ya-dong Gao
Hui Du
Tongji Medical University
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Xiang Dong
Wuhan University Zhongnan Hospital
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Jin-jin Zhang
Wuhan University Zhongnan Hospital
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Yi-yuan Cao
Wuhan University Zhongnan Hospital Department of Radiology
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Mubeccel Akdis
University of Z├╝rich
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Pei-qi Huang
Wuhan Childrens Hospital
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Hong-wei Chen
Wuhan Childrens Hospital
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Ying Li
Wuhan Childrens Hospital
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Guanghui Liu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
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Cezmi Akdis
University of Zurich
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Xiao-xia Lu
Wuhan Childrens Hospital
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Ya-dong Gao
Wuhan University Zhongnan Hospital
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Abstract

The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has made widespread impact recently. We aim to investigate the clinical characteristics of COVID-19 children with different severities and allergic status. Pediatric COVID-19 patients tended to have a mild clinical course. Patients with pneumonia had higher proportion of fever and cough and increased inflammatory biomarkers than those without pneumonia. There was no difference between allergic and non-allergic COVID-19 children in aspects of incidence, clinical features, laboratory and immunological findings. Allergy was not a risk factor for developing and severity of SARS-CoV-2 infection and hardly influenced the disease course of COVID-19 in children.

Peer review status:Published

11 May 2020Submitted to Allergy
11 May 2020Submission Checks Completed
11 May 2020Assigned to Editor
11 May 2020Reviewer(s) Assigned
20 May 2020Review(s) Completed, Editorial Evaluation Pending
21 May 2020Editorial Decision: Revise Minor
24 May 20201st Revision Received
25 May 2020Submission Checks Completed
25 May 2020Assigned to Editor
25 May 2020Reviewer(s) Assigned
28 May 2020Review(s) Completed, Editorial Evaluation Pending
29 May 2020Editorial Decision: Accept
Published in Allergy. 10 Jun 2020. 10.1111/all.14452