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Severe antibody-mediated transfusion-related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non-transfused male blood donor
  • +3
  • Charlotte Agergaard,
  • Thure Haunstrup,
  • Anne-Louise Fjordside,
  • John Baech,
  • Rudi Steffensen,
  • Kaspar Nielsen
Charlotte Agergaard
Vejle Hospital
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Thure Haunstrup
Aalborg University Hospital
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Anne-Louise Fjordside
Aalborg University Hospital
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John Baech
Aalborg University Hospital
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Rudi Steffensen
Aalborg University Hospital
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Kaspar Nielsen
Aalborg University Hospital
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Abstract

Transfusion Related Acute Lung Injury (TRALI) has been associated with neutrophil reacting antibodies in transfused blood products. We report a case of life threatening TRALI in an obstetric patient triggered by transfusion from a non-transfused male blood donor. A residual risk of TRALI exist, even in a male-only plasma setting.

Peer review status:ACCEPTED

10 Jun 2020Submitted to Clinical Case Reports
25 Jun 2020Assigned to Editor
25 Jun 2020Submission Checks Completed
29 Jul 2020Reviewer(s) Assigned
30 Jul 2020Review(s) Completed, Editorial Evaluation Pending
03 Aug 2020Editorial Decision: Accept