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Chronic myeloid leukemia in children and adolescents (A bout 2 cases)
  • +2
  • meryeme abddaoui,
  • ahmed faleh,
  • imane tlemçani,
  • sara ben miloud,
  • moncef amrani hassani
meryeme abddaoui
Hassan II University Hospital in Fez
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ahmed faleh
Hassan II University Hospital in Fez
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imane tlemçani
Hassan II University Hospital in Fez
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sara ben miloud
Hassan II University Hospital in Fez
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moncef amrani hassani
Hassan II University Hospital in Fez
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Abstract

Pediatric chronic myeloid leukemia is a rare entity (2-5% of childhood leukemias) classified as a myeloproliferative neoplasia characterized by the presence of the BCR-ABL fusion gene, the oncogenic translocation product (9; 22) responsible for the disease through its deregulated tyrosine kinase activity.