GuangZe Xu

and 2 more

Background:Radiofrequency catheter ablation(RFCA) has now become the standard and effective therapy for paroxysmal supraventricular tachycardias, but the success rates of ablation were reported different in a large number of single-centers. It is estimated that there are still thousands of cases of relapse in China every year, among which the main cases are of accessory pathways(Aps) mediated tachycardia.Objective: The purpose of this study was to compare the efficacy and safety of two different radiofrequency ablation strategies, improve ablation method and reduce the recurrence rate of ablation of accessory pathway mediated tachycardia.Method and Result: 1712 consecutive cases of AVRT with 1741 accessory pathways were analyzed in our retrospectively observational study. They were divided into group S and group M (undergone complementary ablation) according to different strategies of RFCA. 882 cases with 898 Aps were enrolled in group S versus 830 cases with 843 Aps in group M. The results showed the cumulative recurrence number (rate) at the 1st, 3rd, 6th, 12th, and 24th month after ablation were 4(0.5%) vs 17 (1.9%) p=0.007, 5(0.6%) vs 27(3.0%) p=0.000, 6(0.7%) vs 34 (3.8%) p=0.000, 6(0.7%) vs 58 (6.5%) p=0.000, 7(0.8%) vs 63(7.1%) p=0.000, respectively; Complications of chest pain, over vasovagal reaction, steam pop, angina pectoris, and embolism were rare in both groups; No Valve damage, myocardial infarction, cardiac tamponade, periprocedural death or other serious adverse events occurred in the both groups. Conclusions:The strategy of complementary ablation significantly reduced the recurrence rate of radiofrequency ablation of accessory pathway without increasing the risk of complications.

GuangZe Xu

and 2 more

Introduction: Radiofrequency catheter ablation (RFCA) has become the standard effective therapy for supraventricular tachycardias, but the reported success rates of ablation have differed across a large number of single-center studies. The main reason for tachycardia recurrence is accessory pathway (Ap)-mediated tachycardia, and the RFCA strategy may be related to recurrence. This study aims to compare the efficacy and safety of two different RFCA strategies for Ap-mediated tachycardia. Methods : We compared patients (group M) who underwent RFCA at extensive sites to patients (group S) with RFCA at a single site during the index procedure for Ap-mediated tachycardia. The efficacy and safety were assessed in the two groups. Results: A total of 882 patients with 898 Aps were enrolled in group S, and 830 patients with 843 Aps were enrolled in group M. The results showed that the cumulative numbers of recurrences (rates) at the 1st, 3rd, 6th, 12th, and 24th months after ablation were 4 (0.5%) and 17 (1.9%), p<0.05; 5 (0.6%) and 27 (3.0%), p<0.05; 6 (0.7%) and 34 (3.8%), p<0.05; 6 (0.7%) and 43 (4.8%), p<0.05; and 7 (0.8%) and 45 (5.0%), p<0.05 in group M and group S, respectively. Complications of chest pain, overactive vasovagal reaction, steam pop, and angina pectoris were rare in both groups. No valve damage, cardiac tamponade, or other serious adverse events occurred in either group. Conclusion: The strategy of performing extensive ablation reduced the recurrence rate and need for subsequent ablation of the Ap without increasing the risk of complications.