loading page

Rituximab ameliorated PR3-ANCA positive vasculitis with rheumatoid arthritis simultaneously
  • Akihiro Yamada,
  • Ayuko Sogabe,
  • Yasuaki Okuda
Akihiro Yamada
Dohgo Spa Hospital
Author Profile
Ayuko Sogabe
Dohgo Spa Hospital
Author Profile
Yasuaki Okuda
Dohgo Spa Hospital
Author Profile

Peer review status:UNDER REVIEW

16 Apr 2020Submitted to Clinical Case Reports
01 May 2020Assigned to Editor
01 May 2020Submission Checks Completed
18 May 2020Reviewer(s) Assigned
02 Jun 2020Review(s) Completed, Editorial Evaluation Pending


We treated PR3-ANCA positive vasculitis patient with bilateral ischemic peroneal nerve paralysis accompanying rheumatoid arthritis. Pathology showed mild vasculitis. With PR3-ANCA amelioration, the level of complement 3, anti-CCP and neurological disability normalized simultaneously responding to rituximab. This result means the shared pathogenic pathway of PR3-ANCA vasculitis and rheumatoid arthritis.