Background: Endometriosis is a chronic condition affecting 6-10% of women of reproductive age, with endometriosis-related pain and infertility being the leading symptoms. Currently, the gold standard treatment approach to surgery is conventional laparoscopy (CL); however, the increasing availability of robot-assisted surgery is projected as a competitor of CL. This study aimed to compare the perioperative outcomes of robot-assisted laparoscopy (RAL) and CL in endometriosis surgery. Objectives: We aimed to compare the effectiveness and safety of these two procedures. Methods: A systematic search was conducted in three medical databases. Studies investigating different perioperative outcomes of endometriosis-related surgeries were included. Results are presented as odds ratios (OR) or mean differences (MD) with 95% confidence intervals (CI). Results: Our search yielded 2,014 records, of which 13 were eligible for data extraction. No significant differences were detected between the CL and RAL groups in terms of intraoperative complications (OR=1.07, CI:0.43-2.63), postoperative complications (OR=1.3, CI:0.73-2.32), number of conversions to open surgery (OR=1.34, CI:0.76-2.37), length of hospital stays (MD=0.12, CI:0.33-0.57), blood loss (MD=16.73, CI:4.18-37.63) or number of rehospitalizations (OR= 0.95, CI:0.13-6.75). In terms of operative times (MD=28.09 minutes, CI:11.59-44.59) and operating room times (MD=51.39 minutes, CI:15.07-87.72;), the RAL technique remained inferior. Conclusions: RAL does not have statistically demonstrable advantages over CL in terms of perioperative outcomes for endometriosis-related surgery.

Objective: The aim of the present study was to estimate the effect of viral infections on the development of pregnancy complications and on birth outcome. Design: A population-based retrospective study. Setting and Population: 57,231 control pregnancies (without any birth-defects) were analysed in The Hungarian Case-Control Surveillance of Congenital Abnormalities (HCCSCA). Methods: Associations between viral infection exposures in the 1st trimester of pregnancy and pregnancy complications and birth outcomes were analysed using the non-exposure group as reference, adjusting for maternal age, highest education, and maternal tobacco use. Main Outcome Measures: Quantitative variables such as mean maternal age, birth weight and gestational age and categorical variables like pregnancy complications were evaluated in the group of viral infections and control mothers. Results: In total, 2,238 cases with maternal viral infections during pregnancy were identified in the HCCSCA (influenza: 2,016, enterovirus: 48, herpes simplex: 28, hepatitis B: 22, varicella-zoster: 14, respiratory syncytial virus: 11 and unspecified virus infections: 104). The incidences of threatened abortion (OR: 1.3, 95% CI: 1.2-1.5), threatened preterm birth (OR: 1.4, 95% CI: 1.1-1.7) and anaemia (OR: 1.4, 95% CI: 1.3-1.6) were higher in the mothers of cases. The risk of gestational diabetes was lower in the group of viral infections (OR: 0.4, 95% CI: 0.23-0.9). No significant differences have been detected in preterm birth, birth weight or IUGR between the infected and the control groups. Conclusions: The findings of this study suggest that viral infections during pregnancy do not exert a deleterious effect on birth outcomes.