Amiodarone induced thrombocytopenia is a rare immune mediated hematologic complication of the drug. We describe a case of delayed onset amiodarone induced thrombocytopenia. We highlight the process adopted to arrive at a clinical diagnosis of the same in a 72-year-old male admitted to the hospital with competing causes of thrombocytopenia. Timely diagnosis of drug-induced immune thrombocytopenia is crucial in order to minimize unnecessary testing, avoid treatments with potential harm and prevent life-threatening hemorrhagic complications.