Aslan Demir

and 1 more

Objective Human Papillomavirus (HPV) that is an epitheliotropic virus that infects basal keratinocytes on epithelia of skin and mucosal membranes has been isolated in genital warts (GWs). The relationships between cancer caused by HPV and some vitamins such as B12 and vitamin D and iron metabolism, as well as leukocytes and their ratios have been investigated in the literature. Our aim is to evaluate these relatioships at the level of GW as well as to analyse if there is a relationship between the investigated parameters and lesion numbers. Materials and Methods Data were obtained from 98 and 94 patients for group 1 and 2, including GW patients and healthy people, respectively. The blood parameters and lesion numbers in the GW patients were reported and analysed in terms of vitamin B12 and D, ferritin and leucocytes. Results A correlation was established between lesion numbers, age and midcorpusculer volume (MCV) (p<0.05). There was no any correlation between lesion numbers and recurrent cases. According to the comparative analysis, there were a difference in terms of ferritin, neutrophil, monocyte, hemoglobine, MCV and neutrophil/monocyte ratio between groups. The cutoff values for neutrophil, monocyte and N/M ratios were 56.45, 4.91, and 7.825, respectively Conclusion While our study showed that GW development may be affected by blood ferritin levels and in this situation, MCV, neutrophil, monocyte and N / M ratios may change, a relation was found between lesion numbers and age and mean MCV values only. However, further studies are needed to clarify this issue.

Kadir Gunseren

and 4 more

Objectives To investigate the operation time (OT) and the ureteral access sheath (UAS) usage with the infection rates and to determine a cut-off value for OT Methods We retrospectively analyzed the data of the patients who underwent FURS for renal stones larger than 20 mm between 2010 and 2019. The investigated parameters were OT, UAS using, and infection status. The data were analyzed by forming two groups according to whether the OT was less than 60 minutes and more, whether the UAS was used and whether an infection occurred. In addition, independent risk factors that may affect postoperative urinary infection development were also investigated by logistic regression analysis. And, a ROC curve analysis was applied to determine a cut-off value in OT terms, where infection rates increase more. Results A total of 575 patients were enrolled in the study. The rates of the usage UAS and infection were greater statistically in the group for longer than 60 minutes. OT was longer statistically in the infection group than in the group without infection ( 94.1±14.2 and 68.01±23.1, for groups 1 and 2, respectively, p<0.05, Table 2). OT was statistically longer in the UAS group than unused one ( 79.3±24.4 and 66.7±22.4, for groups 1 and 2, respectively, p<0.05, Table 3). ROC analyses revealed a cut-off point of 87.5min for OT in terms of infection rate Conclusion While the infection risk increases when OT exceeds 60 minutes, FURS can be safely performed up to 87.5 minutes with 89% sensitivity and 69% specificity infection risk.