Aims of the study: We aimed to investigate the effects of TAS2R38 (bitter taste gene) and TAS1R2 (sweet taste gene) gene polymorphisms, which are the most important members of the Tat gene family, on the dental status of obese and normal-weight children. Methods used to conduct the study: The study included 78 healthy children and 100 children diagnosed with obesity (5 - 16 years old). Anthropometric measurements and the dental status of the children were evaluated. The DMFT/dmft index of teeth was determined, using standards methods recommended by world health organization. Blood samples were collected from all subjects and were analyzed via PCR using specific primers for the genetic analyses. Five single nucleotide polymorphisms (SNPs) indicating TAS2R38 gene and TAS1R2 polymorphisms were investigated. Truncate poisson and truncate negative binomial modeling approach used with the data. Results of the study: DMFT score was low in obese children and it was high in children who doesn’t sense bitter taste (non-taster). While obese non-taster children had increased DMFT scores, normal weighted non-taster children had decreased DMFT scores. Conclusions drawn from the study and clinical implications: The alanine, valine, and isoleucine (AVI), as well as the proline, alanine, and valine haplotypes (PAV), of the TAS2R38 gene are associated with DMFT score and obesity. What’s Now: It is known that the sense of taste affects nutrition. Moreover, nutrition is associated with caries and obesity. What’s New: The authors studied caries and obesity along with taste genes in this study. There are little studies in the literature that study obesity, decay and taste genetics together, and this study clarifies this issue in three ways. At the same time, an effort was given to the statistical analysis part Keywords: Oral health, childhood obesity, tooth decay, TAS2R38 polymorphism, diet, genetic

Aim: The present study compares the effectiveness of four different remineralization agents on the demineralized enamel of permanent human incisors. The purpose of this study is to evaluate the effectiveness of remineralization agents on the initial enamel lesion. Material- Methods: Crowns affected by demineralization were divided into two equal parts. The right halves of the teeth were subjected to no other processes after demineralization for control purposes and were kept in artificial saliva for the duration of the experiment. The left halves of the crowns were remineralized using a 5% NaF-containing fluoride varnish (GC MI Varnish GC Corp, Tokyo, Japan), a casein phosphopeptide and amorphous calcium toothpaste (GC Tooth Mousse, GC Corp, Tokyo, Japan), fluoride, hydroxyapatite, and xylitol, containing a water-soluble remineralization paste (Remin Pro™, Voco, Germany) and calcium, magnesium and phosphate-containing gel (Medical Remineralizing gel (R.O.C.S. Trading GmbH, Munich, Germany). After a 21-day remineralization process, and SEM/EDX analysis was performed, and a One Way Anova was used for statistical analysis. Results: According to EDX analysis, the R.O.C.S. medical remineralizing gel was found to have a lower Ca/P ratio than the other material groups (p =0.04). Remin Pro™, Voco, and the R.O.C.S. were higher than the control group in evaluating the Ca / P ratio (p=0.014), (p=0.025). Conclusions: The R.O.C.S group, treated with fluoride-free xylitol-containing, a remineralization agent, showed the lowest Ca/P ratio. Compared to demineralized halves of the teeth (control groups), Remin Pro™, Voco, and R.O.C.S. medical remineralizing gel may be considered as affecting on initial enamel lesions. Key Words: Remineralizing Agents, EDX, SEM, Enamel,