Somayeh Sadeghi

and 12 more

Introduction: The unrelenting storm of coronavirus disease (COVID-19) since late 2019 has turned into a crucial health matter of the globe. There is increasing evidence in terms of a hypercoagulable state by this infection. Therefore, the current study aims to clarify the association between thromboembolic events in COVID-19 and the patient, the infection, and in-hospital related characteristics. Methods: The current case-control study has been conducted on 243 COVID-19 pneumonia patients (83 cases with thrombotic events and 160 controls without thrombosis) in 2020. The thrombotic events included deep venous thrombosis (DVT) (n=9), pulmonary thromboembolism (PTE) (n=48), acute myocardial infarction (AMI) (n=17), cerebrovascular accidents (CVA) (n=4) and arterial thrombosis (n=5). On admission, hemodynamic parameters, on admission laboratory assessments, mobility during hospitalization, type of oxygenation, intensive care unit (ICU) admission requirement, duration of ICU and hospital stay were recorded in the checklist. Results: According to logistic regression assessment, on admission O2 saturation (OR: 0.97, 95%CI: 0.94-0.99), hemoglobin level (OR: 0.87, 95%CI: 0.77-0.97) and albumin level (OR: 0.53, 95%CI: 0.3-0.86) were independently correlated with thrombosis due to COVID-19. Other factors, including demographic, infection severity, laboratory and in-hospital characteristics, were not significantly associated with thrombotic events. Conclusion: Based on this study’s findings, hemoglobin and albumin levels were the independent factors associated with the thrombotic events in COVID-19 patients.